The ERJ-145 is a regional jet manufactured by Embraer, a Brazilian aerospace company. Family members of the Embraer include the ERJ 135, ERJ 140, and ERJ 145, as well as the Legacy business jet and the R-99 family of military aircraft. The ERJ 145 is the largest of the group. Each jet in the series is powered by two turbofan engines. The family's primary competition comes from the Canadair Regional Jets.

The ERJ-145 could accommodate 50 passengers in a three abreast seating configuration and it has a range of about 2500 km. In late 1991, the Embraer ERJ 145 design was frozen, now with rear mounted engines. It did keep some features from the Brasilia such as the three abreast seating (2+1). The first flight was on August 11, 1995, with the first delivery in December, 1996, to Expressjet, then the regional division of Continental Airlines (and spun off in 2002 as a separate company, ExpressJet Airlines, NYSE: XJT). Expressjet, doing business as Continental Express, is by far the largest operator with 255 of the nearly 1000 ERJ 145 in service. The second largest operator is American Eagle with 107 ERJ 145 aircraft. The Brazilian military operates the (Embraer) EMB-145 under the designation C-99A. It also operates the R-99 models A and B, which are both derived from the EMB-145. Embraer retains the "EMB-" prefix when referring to its military models.

Since mid 2004, the ERJ-145 is also assembled in China by Harbin Embraer.